All the children of Muḥammadsa were from Khadījahra, except Ibrahīmas who was conceived by Māriyah Qibṭiyyahra, during the latter age of Muḥammadsa. From Ḥaḍrat Khadījahra, Muḥammadsa was given three sons named Qāsimas, Ṭāhiras and Ṭayyabas. In some narrations, a young boy named ‘Abdullāhas is also mentioned. However, it is a generally accepted notion that ‘Abdullāhas was the second name given to Ṭayyabas. Among his daughters were Zainabra, Ruqayyahra, Ummi Kulthūmra and Fāṭimahra. All the children of Muḥammadsa from his wife Khadījahra, were born prior to his claim to prophethood and thus according to the Arabian custom, Muḥammadsa received the appellation Abul-Qāsim after the name of his eldest son, named Qāsim.
All of the sons of Muḥammadsa passed away in childhood. However, all of his daughters grew to adulthood and accepted Islām. The progeny of none of his daughters lived on except for his youngest daughter Fāṭimatuz-Zahrāra. His eldest daughter, Zainabra, was married to Abul-‘Ās bin Rabī‘ who was one of the relatives of Ḥaḍrat Khadījahra. Zainabra bore Abul-‘Ās a son named ‘Alī and a daughter named ’Umāmahra. The son died in infancy, but the daughter grew old and was married to Ḥaḍrat ‘Alira after the demise of Ḥaḍrat Fāṭimahra. However, the progeny of ’Umāmahra did not live on. Muḥammadsa held ’Umāmahra very dear to himself. Abul-‘Āsra did not accept Islām for many years after the Ḥijrah to Madīnah due to which Zainabra was subjected to various hardships. Zainabra passed away in the life time of the Holy Prophetsa.
Ruqayyahra and Ummi Kulthūmra were married to the two sons of the paternal uncle of Muḥammadsa named Abū Lahab. Their names were ‘Utbah and ‘Utaibah. However, in the age of Islām when Abū Lahab began to fiercely oppose the Prophetsa their marriages were nullified prior to the finalization of their marriage. After this Ruqayyahra and Ummi Kulthūm came into the matrimonial tie of Ḥaḍrat ‘Uthmān bin ‘Affānra one after the other. This is why he is also referred to as Dhun-Nūrain, which means ‘The Possessor of Two Lights’. However, the progeny of both these noble ladies did not advance. Ruqayyahra had a son ‘Abdullāhas who passed away and Ummi Kulthūmra had no children at all. Ruqayyahra passed away during the time period of the Battle of Badr and Ummi Kulthūmra died after the Fall of Makkah.
Fāṭimahra, who was the youngest daughter of Muḥammadsa, was most dear to him. After the migration, she was given in marriage to Ḥaḍrat ‘Alīra from whom two sons, Ḥasanra and Ḥusainra were born. Their descendants are known as ‘Syed’. Ḥaḍrat Fāṭimahra passed away six months subsequent to the demise of the Holy Prophetsa.1 The children of Ḥaḍrat Khadījahra from her first two husbands were two sons named Hind and Hāllah as well as a daughter named Hind. By the grace of God, all of them accepted Islām.
1 * As-Sīratun-Nabawiyyah, By Abū Muḥammad ‘Abdul-Malik bin Hishām, Dārul-Kutubil-‘Ilmiyyah, Beirut, Lebanon, First Edition (2001)
* Aṭ-Ṭabaqātul-Kubrā, By Muḥammad bin Sa‘d, Volume 8, Dhikru Banāti Rasūlillāhisa - Fāṭimata binti Rasūlillāhsa, p. 257, Dārul-Iḥyā’it-Turāthil-‘Arabī, Beirut, First Edition (1996)
* Sharḥul-‘Allāmatiz-Zarqānī ‘alal-Mawāhibil-Ladunniyyah, By Muḥammad bin ‘Abdul-Bāqī Az-Zarqānī, Volume 4, p. 336, Bābun Fī Dhikri Aulādihil-Kirām, Dārul-Kutubil-‘Ilmiyyah, Beirut, Lebanon, First Edition (1996)